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Hannah E Salapa Selected Research

Heterogeneous Nuclear Ribonucleoprotein A1

1/2022Autoimmunity to a ribonucleoprotein drives neuron loss in multiple sclerosis models.
11/2021Knock-Down of Heterogeneous Nuclear Ribonucleoprotein A1 Results in Neurite Damage, Altered Stress Granule Biology, and Cellular Toxicity in Differentiated Neuronal Cells.
1/2021A Comprehensive Analysis of the Role of hnRNP A1 Function and Dysfunction in the Pathogenesis of Neurodegenerative Disease.
1/2020Antibodies to the RNA binding protein heterogeneous nuclear ribonucleoprotein A1 contribute to neuronal cell loss in an animal model of multiple sclerosis.
1/2019Localization of near-infrared labeled antibodies to the central nervous system in experimental autoimmune encephalomyelitis.
11/2018Dysfunctional RNA binding proteins and stress granules in multiple sclerosis.
4/2016Antibodies to the RNA Binding Protein Heterogeneous Nuclear Ribonucleoprotein A1 Colocalize to Stress Granules Resulting in Altered RNA and Protein Levels in a Model of Neurodegeneration in Multiple Sclerosis.
1/2016Antibodies to the RNA-binding protein hnRNP A1 contribute to neurodegeneration in a model of central nervous system autoimmune inflammatory disease.

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Hannah E Salapa Research Topics

Disease

11Multiple Sclerosis
01/2022 - 01/2016
5Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2022 - 01/2016
4Neurodegenerative Diseases (Neurodegenerative Disease)
11/2021 - 11/2018
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2021 - 01/2020
1Huntington Disease (Huntington's Disease)
01/2021
1Spinal Muscular Atrophy (Progressive Muscular Atrophy)
01/2021
1Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
01/2021
1Alzheimer Disease (Alzheimer's Disease)
01/2021
1Neoplasms (Cancer)
01/2021
1Mitochondrial Diseases (Mitochondrial Disease)
06/2020
1Neuroinflammatory Diseases
06/2020
1Frontotemporal Dementia (Semantic Dementia)
01/2020
1Paralysis (Palsy)
01/2019
1Autoimmune Diseases (Autoimmune Disease)
01/2019
1Paraplegia (Spastic Paraplegia)
04/2016

Drug/Important Bio-Agent (IBA)

8Heterogeneous Nuclear Ribonucleoprotein A1IBA
01/2022 - 01/2016
8RNA-Binding Proteins (RNA-Binding Protein)IBA
06/2020 - 01/2016
5AntibodiesIBA
01/2022 - 01/2016
3Proteins (Proteins, Gene)FDA Link
03/2021 - 04/2016
2RibonucleoproteinsIBA
01/2022 - 03/2021
2RNA (Ribonucleic Acid)IBA
01/2020 - 04/2016
1Immunodominant EpitopesIBA
01/2022
1Immunoglobulin G (IgG)IBA
01/2022
1CryptochromesIBA
03/2021
1Biological ProductsIBA
01/2019
1Matrix Metalloproteinases (MMPs)IBA
01/2019
1AutoantibodiesIBA
01/2016
1AntigensIBA
01/2016
1Myelin-Oligodendrocyte GlycoproteinIBA
01/2016

Therapy/Procedure

1Therapeutics
03/2021